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Hair Loss Patent

Halogenated pyrimidine 3-oxide derivatives, their use for the treatment and prevention of hair loss and for stimulating its regrowth

The invention relates to compounds of formula: ##STR1## in which: R.sub.1 and R.sub.2 denote, independently of one another, a hydrogen atom or alternatively a carbamoyl group of formula: ##STR2## with R'.sub.3 denoting hydrogen or R.sub.3 ; an alkoxycarbonyl group of formula: ##STR3## or an acyl group of formula: ##STR4## in which formulae R.sub.3 denotes an alkyl, alkenyl or cycloalkyl radical; R.sub.3 can also denote an aryl or aralkyl radical; and R denotes a linear or braanched C.sub.1 -C.sub.8 alkyl radical substituted with one or more halogen atoms, and to their use for the treatment and prevention of hair loss and for stimulating its regrowth.

Nutrient composition for preventing hair loss


A combination intended to induce and stimulate hair growth and reduce hair loss comprising a first component containing at least one calcium antagonist in a physiologically acceptable medium and a second component containing, in a physiologically acceptable medium, at least one pyrimidine derivative having the formula: ##STR1## In formula (I) R.sub.1 represents the group ##STR2## in which R.sub.3 and R.sub.4 are independent of each other and represent hydrogen, an alkyl, alkenyl, alkylaryl or cycloalkyl group, or R.sub.3 and R.sub.4 form a heterocycle with the nitrogen atom joined

Combination of pyrimidine derivatives and calcium antagonists to induce and stimulate hair growth and reduce hair loss


A combination intended to induce and stimulate hair growth and reduce hair loss comprising a first component containing at least one calcium antagonist in a physiologically acceptable medium and a second component containing, in a physiologically acceptable medium, at least one pyrimidine derivative having the formula: ##STR1## In formula (I) R.sub.1 represents the group ##STR2## in which R.sub.3 and R.sub.4 are independent of each other and represent hydrogen, an alkyl, alkenyl, alkylaryl or cycloalkyl group, or R.sub.3 and R.sub.4 form a heterocycle with the nitrogen atom joined thereto, and represent an aziridinyl, azetidinyl, pyrrolidinyl, piperidinyl, hexahydroazepinyl, heptamethyleneimine, octamethyleneimine, morpholine or 4-alkylpiperazidinyl group, the heterocyclic groups further being substitutable at the carbon atoms by one to three low alkyl, hydroxy or alkoxy groups. In formula (I) R.sub.2 represents a hydrogen atom, an alkyl, alkenyl, alkylalkoxy, cycloalkyl, aryl, alkylaryl, arylalkyl, alkylarylalkyl, alkoxyarylalkyl or haloarylalkyl group. The addition salts of physiologically acceptable acids may also be employed. The first and second components may form part of the same composition or may be used separately, either simultaneously or in successive or separate stages.

24-diaminopyrimidine 3-oxide derivatives and their use for the treatment and prevention of hair loss

New 2,4-diaminopyrimidine 3-oxide derivatives and their use for the treatment and the prevention of hair loss. The compounds correspond to the formula: ##STR1## in which: R.sub.1 and R.sub.2 denote hydrogen or the groups of formula: ##STR2## with R'.sub.3 =H or R.sub.3, in which R.sub.3 denotes alkyl, alkenyl or cycloalkyl; R.sub.3 may also denote an aryl or aralkyl radical. R denotes alkyl, alkenyl or cycloalkyl capable of bearing an unsaturation or alkyl bearing an aromatic or heterocyclic nucleus.


Photodynamic therapy for the treatment of hair loss
Nutrient composition for preventing hair loss
Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins

51 5132106 Halogenated pyrimidine 3-oxide derivatives, their use for the treatment and prevention of hair loss and for stimulating its regrowth
52 5122369 Nutrient composition for preventing hair loss
53 5059606 Combination of pyrimidine derivatives and calcium antagonists to induce and stimulate hair growth and reduce hair loss
54 4973474 24-diaminopyrimidine 3-oxide derivatives and their use for the treatment and prevention of hair loss
55 4966173 Hairpiece for compensation of hair loss
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